Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms. Remain up to date on recent discoveries and revelations through these webinars.
The disposition of antibody-based therapeutics is generally determined by both target-mediated and non-target processes, the latter being an often-overlooked aspect. Target-independent liabi...
A microphysiological system is a 3D in vitro model that mimics human tissue environments with high physiological relevance. This approach enhances our understanding of disease mechanisms, dr...
Numerous biomedical applications have been described for liver-humanized mouse models, such as in drug metabolism or drug-drug interaction (DDI) studies. However, the strong enlargement of t...
One of the primary limitations in drug discovery and toxicology research is the lack of good model systems between the single cell level and animal or human systems. This is especially true...
Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell. Analysis...
Organisms sense and respond to changes in the environment through signal transduction pathways. Pathways like highly conserved Mitogen-Activated Protein Kinase (MAPK) pathways are composed o...
1) Microscope slides and coverglass are used in many parts of the lab while knowledge of how these items are made and the technical properties they have is limited. 2) By not understanding t...
Join Dr. Steben and Dr. Riedel in their discussion of the HPV landscape and the shift to primary screening. Dr. Steben will set the scene with a discussion of: HPV prevention and prevalence...
Neural organoids derived from patient-specific iPSC lines can help open doors toward studying human brain development, physiology, and disease progression. The increased cell-cell interacti...
Spatial transcriptomics offers a revolutionary approach to understanding the tumor microenvironment (TME) in solid tumors by preserving the spatial context of gene expression, which is cruci...
High-resolution spatial transcriptomics stands at the forefront of technological advancements, offering transformative capabilities in the domain of tumor biology research. In this presentat...
Precise protein quantification is a crucial step in workflows involving protein extraction, isolation, and analysis. Accurate knowledge of the concentration of your protein sample is essenti...
Antibodies against ribonucleoprotein (RNP) are an important serologic marker for mixed connective tissue disease (MCTD). RNP interacts with Smith (Sm) proteins to form the Sm/RNP complex. An...
Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells are widely used in the biotechnology industry for production of a wide range of therapeutics, predominantly monoclona...
Self-removing affinity tags have the potential to greatly accelerate the development of new therapeutics, while providing a potentially enabling manufacturing platform for non-mAb therapeuti...
Chimeric antigen receptor T-cell (CAR-T) therapies have emerged as a revolutionary approach in the field of hematological malignancies, offering unprecedented clinical efficacy when patients...
Nanoparticle mRNA Therapeutics has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2024, there are two mRNA vaccines approved...
Efficient utilisation of abundant renewable sugars and aromatic chemicals by natural or recombinant microorganisms is a key prerequisite for the economic viability of biotechnological valori...
Effective process development for viral vector-based medicines is paramount for optimized process efficiency, robustness, scalability, and product quality. Well-designed processes streamline...
In the slowly evolving landscape of bioprocess development and manufacturing, digital bioprocess-twins have emerged as potential accelerators. While advanced algorithms are at the heart of t...
Join us in this enlightening session to deepen your understanding of qualifications and their transformative impact on risk management and regulatory adherence. Gain actionable insights that...
It is over half a century since haemoglobin A1c (HbA1c) was recognised by medical professionals; the importance of HbA1c to the long term health of people with diabetes was clearly demonstra...
Tissue microarray combines tens to hundreds paraffin-embedded specimens into a single paraffin block. It is a practical and highly effective tool for high-throughput analyses including valid...
Endonuclease Cas12a, as one key part of the CRISPR/Cas biotechnology, possessed a unique dual enzymatic function which has been widely used for various applications1. However, the limits tra...
Molecular diagnostics based on clustered regularly interspaced short palindromic repeats (CRISPR) enzyme systems have been the subject of intense research....
Rather than being famous in gene editing field only, by revealing the collateral cleavage activity of Cas12a, Cas13a, Cas14 effectors, and more, Clustered Regularly Interspaced Short Palindr...
Organoids continue to gain traction in drug discovery efforts as they offer a more biologically relevant disease model than traditional approaches. But they aren't without challenges. Jo...
The disposition of antibody-based therapeutics is generally determined by both target-mediated and non-target processes, the latter being an often-overlooked aspect. Target-independent liabi...
