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BOC Sciences specializes in small molecule synthesis, biosynthesis, purification, and characterization. It provides a wide range of research chemicals and biochemicals, including inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP Products, impurities and metabolites, APIs, natural compounds, ADCs, stem cell molecules and chiral compounds.
BOC Sciences
(Gln22)-Amyloid _-Protein (1-40) | BOC Sciences
(Gln22)-Amyloid _-Protein (1-40) is a Dutch mutation (E22Q) of amyloid _-peptide that aggregates more readily than the wild-type peptide, and the resulting fibrils show increased neurotoxicity. At the concentration of 25 _m, the mutant peptide E22Q could induce apoptosis of brain endothelial cells, but WT A_ 1-40 and the Italian mutant E22K had no significant effect on apoptosis.
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