New Transfection Kit

XPMagis a novel magnetic nanoparticles formulation dedicated to gene transfection in organotypic cultures of explant by “Reverse Magnetofection”.

“Reverse Magnetofection” provides a novel and non-toxic strategy for nucleic acids (DNA & siRNA) based gene therapy in the retina that can be translated to a wide variety of organ explants.

XPMagassociated with Reverse Magnetofection allows the delivery of nucleic acids (NA) up to the deepest explant layers.

The magnetic force, delivered by a specific magnetic plate, guides and concentrates complexes of NA and XPMag magnetic nanoparticles from the culture media to the tissue. This novel method of transfection associating XPMag and Reverse Magnetofection is fully biocompatible and does induce neither apoptosis nor inflammatory reactions.

XPMag transfection reagent /

MAIN BENEFITS:

Highly efficient with microglial cell lines & primary cells

Low nucleic acid amount - minimized toxicity

High level of nucleic acid compaction

Easy and straightforward protocol

Compatible with any culture medium./

Sizes :

XP00250: 250 µL of XPMag reagent

XP00500: 500 µL of XPMag reagent

KXP0250: XPMag Starting Kit - 250 µL of XPMAg reagent + Super Magnetic Plate